January 30, 2003, 3:20 PM
New Study Shows Tea Extract Protects Skin; White Tea Extract Reveals Anti-cancer, Anti-aging Properties
ScienceDaily (Jan. 30, 2003)
— Cleveland (January 27, 2003) -- Scientists at University Hospitals of
Cleveland and Case Western Reserve University have proven that
ingredients in white tea are effective in boosting the immune function
of skin cells and protecting them against the damaging effects of the
sun. The discovery that white tea extract protects the skin from
oxidative stress and immune cell damage adds another important element
in the battle against skin cancer.
Elma Baron, MD, is Director of the Skin Study Center at UHC and
CWRU. "We found the application of white tea extract protects critical
elements of the skin's immune system, " Dr. Baron says. "Similar to the
way oxidation causes a car to rust, oxidative stress of the skin causes
a breakdown in cellular strength and function. The white tea extract
protects against this stress. This study further demonstrates the
importance of researching how plant products can actually protect the
skin." Dr. Baron worked with Seth Stevens, MD, principal investigator
for the study.
As part of the study, scientists applied a white tea extract cream
to one patch of skin on the subject's buttock (skin that is not
ordinarily exposed to much sunlight), while another area was left
unprotected. Both areas were then exposed to artificial sunlight.
Researchers then reapplied the white tea extract to the area previously
coated. Three days later the scientists compared the patches of skin on
a cellular level.
Here's what they looked for: In the immune system, the Langerhans
cells in the outer layer of the skin (epidermis) are the outermost
reach of the immune system, and are the first to recognize foreign
agents. They are the sentinel cells or watchdog cells, essential in
detecting germs and mutated proteins produced by cancerous cells; but,
because of their location, the Langerhans cells are very sensitive to
damage by sunlight. Scientists in the study found the white tea extract
protected against the Langerhans cell obliteration that was observed in
the sun-exposed skin not treated with the extract. The investigators
then tested whether the preserved immune system cells in the white tea
extract-protected skin would still function properly after exposure to
sunlight; they discovered the immune function was indeed restored by
the extract. They also found that the DNA damage that can occur in
cells after exposure to sunlight was limited in the skin cells
protected by the white tea extract.
Researchers believe that white tea extract's anti-oxidant properties
are the reason the extract was effective; if so, it also suggests that
the agent may provide anti-aging benefits. The same process of
oxidative stress in skin cells that leads to immune system damage can
also promote skin cancer and photo damage, such as wrinkling or mottled
pigmentation.
Kevin Cooper, MD, is chairman of the department of dermatology at
UHC and CWRU. "We know that younger skin tends to be able to resist the
oxidative stress associated with exposure to the destructive rays of
sunlight. The white tea extract also appears to build the skin's
resistance against stresses that cause the skin to age."
The results offer promise in the battle against skin cancer, the
most common form of cancer in the United States with more than one
million new cases diagnosed every year.
The Skin Study Center at UHC and CWRU has studied the benefits of
another form of tea that has protective effects. Researchers found that
ingredients in green tea decreased the direct effects of sunburn. This
newest study is the first of its kind involving white tea. White and
green teas contain the highest amounts of antioxidants of all tea
varieties, but white tea is actually the least processed form of tea
and is rarely used in consumer products.
Article source: http://www.sciencedaily.com/releases/2003/01/030130081227.htm